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NIHR MRes/PhD Studentships - Basic Science

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Newcastle University
28 March 2012
Professor Zofia Chrzanowska-Lightowlers

Further information

NIHR MRes/PhD Studentships - Basic Science

Newcastle Universities Faculty of Medical Science has adopted research on ageing as its overarching priority theme. Further, the University’s excellence in this area was recognised through the 2011 NIHR award (£21 million) for a Biomedical Research Centre in Ageing and a Biomedical  Research Unit in Dementia. As part of this we recognise the importance of developing research  capacity in ageing research and are offering upto 13 MRes/PhD projects. These will be in the following areas of ageing and age-related disease research and will be awarded to potential PhD students who show a strong desire to help us better understand the processes of ageing.
Successful students will join Newcastle University and the NIHR Training School.
4 years integrated MRes/PhD or 3 years PhD if applicant has a suitable Masters Degree approved by Newcastle University.

• Development of laser-capture microscopy for the phenotypic profiling of myofibroblasts in diseased   human liver - Professor Derek Mann 
• Induction of plastic changes in reticulospinal output  by neurostimulation - Professor Stuart Baker 
• Identification of new ways to maintain and restore cell defence and repair systems during ageing -   Dr Elizabeth Veal
• The use of biomarkers to aid the management of elderly people with bacteriuria - Dr Philip Aldridge
• Motor neuron loss and disease in normal ageing - is this the key to sarcopenia? - Professor Doug Turnbull
• Identifying novel mitochondrially-active drugs through medium-through-put screening -   Professor Patrick Chinnery
• Genetics, epigenetics and expression in osteoarthritis, the GEE_OA study - Professor John Loughlin

• Understanding the functions of sumoylation in stress responses and longevity - Professor Brian Morgan
• The link between copper homeostasis and Alzheimer’s disease as a route to therapy -   Professor Chris Dennison
• Copper chelation as a treatment to inhibit hepatic fibrosis - Dr Julian Rutherford
• Investigation into the mechanisms underlying ageassociated increases in susceptibility to fungal   infections - Dr Janet Quinn
• P62 accumulation and aggregation as a target for diagnostics and intervention in age-related   neurodegenerative disease - Dr Viktor Korolchuk
• Novel epithelia innate immune mechanism and its relationship to age-related gastro-intestinal   inflammatory diseases: A new therapeutic target? - Professor Brendan Kenny

To Apply you must complete the University’s online postgraduate application form. Select “Master of
Research/Doctor of Philosophy (Medical Sciences) - Ageing and Health” as the programme of study.
Only mandatory fields need to be completed (no personal statement required) but you must quote
reference number IA052 in the personal statement section and also attach a copy of the transcript
from your current course in addition to a CV and a covering letter. For further information please
contact Professor Zofia Chrzanowska-Lightowlers (

Closing date: 18 May 2012.

Committed to Equal Opportunities

Newcastle Biomedical Research Centre

Newcastle University

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