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BBSRC MRes/PhD Studentship: Stem Cells and Arterial Wall Regeneration
- Doctoral Training Partnership (DTP)
- Reference Code: HG041
Name of the supervisors
Prof. Deborah Henderson , Institute of Genetic Medicine
Dr Bill Chaudhry , Institute of Genetic Medicine
This studentship is sponsored by BBSRC as part of the Doctoral Training Partnership (DTP)
Duration of the award
4 years (one year MRes followed by a three year PhD)
This project is a component of an integrated programme of work focussing on the molecular and embryological mechanisms that underlie cardiovascular development.
We are investigating whether the embryonic origins of the cells that make up the great arteries is relevant to cardiovascular diseases affecting the adult, including aortic valve disease, aneurysm and atherosclerosis.
In this studentship the student will establish the origin of cardiac progenitors (stem cells) found in the adult arterial wall and also determine whether they are associated with a specific "extracellular niche". They will then determine whether either or both of these are disrupted in diseased and aging vessels. Finally, the student will investigate whether manipulating either the stem cell populations of their extracellular environment can lead to vessel wall regeneration.
The student will be based at the Institute of Genetic Medicine, Newcastle University. The student will learn a range of skills/techniques including mouse genetics, mRNA and protein expression analyses, cell culture and state-of the-art imaging methodologies. They will join a thriving and well-funded research team, which puts great emphasis on scientific training and the development of transferrable skills.
A high level of self-motivation, good team working skills, meticulous attention to detail and an enthusiastic approach to your work are essential.
Value of the Award and Eligibility
Depending on how you meet the BBSRC's eligibility criteria, you may be entitled to a full or a partial award. A full award covers tuition fees at the UK/EU rate and an annual stipend of £13,590 (2011/12). A partial award covers fees at the UK/EU rate only.
The successful applicant will have Upper 2nd Class or 1st Class degree in Biological Sciences and have an interest in developmental biology and stem cells/regeneration.
How to Apply
You must complete the University's postgraduate application form . Select "Master of Research/Doctor of Philosophy (Medical Sciences) - Human Genetics" as the programme of study. Only mandatory fields need to be completed (no personal statement required) and a covering letter, CV and (if English is not your first language) a copy of your English language qualifications must be attached. The covering letter must state the title of the studentship, quote the reference number HG041 and state how your interests and experience relate to the project.
You should also send your covering letter and CV to Prof. Deborah Henderson ( firstname.lastname@example.org ).
Closing date for applications
Prompt application is advised as this post is only available until a suitable candidate is appointed.
For informal enquiries please contact:
Prof. Deborah Henderson ( email@example.com )
Dr Bill Chaudhry ( firstname.lastname@example.org )