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The Immunological Bioinformatics group, headed by Prof. Ole Lund, within the Center for Biological Sequence Analysis at the Technical University of Denmark is seeking highly motivated candidates for two PhD positions within machine learning methods in systems biology. For exceptional candidates a postdoc position may be offered. Successful candidates will work in a dynamic team developing tools, implementing methods, and applying techniques and procedures for high-throughput epitope analysis.
One candidate will be responsible for implementing and developing improved methods for prediction of peptides binding to MHC class I and II molecules, development of methods for prediction of immune dominance and T cell cross reactivity, and developing methods for predicting antigenic/epitope rich proteins based on systems biology approaches.
The other candidate will be responsible for implementing and developing different machine learning based methods for interpreting FACS (Fluorescence-activated cell sorting) data, predicting of MHC-peptide-TCR interactions, and analyzing imprints on T cell cross reactivity on epitope escape.
Applicants should hold a masters degree in bioinformatics, biology, engineering, computer science or similar. The candidate must have strong computational skills and prior experience with Unix/Linux command line environments, as well as either Perl, Python, Ruby or a comparable scripting language. The applicant must have prior experience with bioinformatics and machine learning methods. Knowledge of systems biology, immunology, and structural biology is considered a plus. The applicant must be a good communicator and strong in written as well as spoken English.
Approval and Enrolment
The scholarships for the PhD degree are subject to academic approval, and the candidates will be enrolled in one of the general degree programmes of DTU. For information about the general requirements for enrolment and the general planning of the scholarship studies, please see the DTU PhD Guide.
Salary and appointment terms
The salary and appointment terms are consistent with the current rules for PhD degree students. The period of employment is 3 years.
Further information may be obtained from Prof. Ole Lund, firstname.lastname@example.org.
Do NOT send applications to this e-mail address, but use the electronic submission system - see below!
We must have your online application by 1 June 2012. Please apply for the positions at www.dtu.dk/career - open the link "apply for this job online", fill in the application form and attach the following documents;
• A letter motivating the application (cover letter)
• Curriculum vitae
• Contact information for 2 references
• Brief description of research experience & interests
• Grade transcripts and BSc/MSc diploma
• Excel sheet with translation of grades to the Danish grading system (see guidelines and excel spreadsheet here)
Candidates may apply prior to obtaining their master's degree, but cannot begin before having received it.
All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.
The Center for Biological Sequence Analysis at the Technical University of Denmark was formed in 1993, and conducts basic research in the fields of bioinformatics and systems biology. The center is divided into twelve specialist research groups, has a highly multi-disciplinary profile (biologists, biochemists, MDs, physicists, statisticians, and computer scientists) with a ratio of 2:1 of bio-to-nonbio backgrounds. CBS represents one of the large bioinformatics groups in academia in Europe.